Commentary: Neurotransmitter Secretion and Cell Signaling
نویسندگان
چکیده
منابع مشابه
Visualizing neurotransmitter secretion at individual synapses.
To advance understanding of the brain, the ability to measure both nerve cell electrical spiking and chemical neurotransmission with high spatial resolution is required. In comparison to the development of voltage sensors and Ca(2+) indicator dyes over the past several decades, high resolution imaging of neurotransmitter (NT) release at single synapses has not been possible. In this Viewpoint, ...
متن کاملQuantal neurotransmitter secretion rate exhibits fractal behavior.
The rate of exocytic events from both neurons and non-neuronal cells exhibits fluctuations consistent with fractal (self-similar) behavior in time, as evidenced by a number of statistical measures. We explicitly demonstrate this for neurotransmitter secretion at Xenopus neuromuscular junctions and for rat hippocampal synapses in culture; the exocytosis of exogenously supplied neurotransmitter f...
متن کاملNeurotransmitter signaling in white matter.
White matter (WM) tracts are bundles of myelinated axons that provide for rapid communication throughout the CNS and integration in grey matter (GM). The main cells in myelinated tracts are oligodendrocytes and astrocytes, with small populations of microglia and oligodendrocyte precursor cells. The prominence of neurotransmitter signaling in WM, which largely exclude neuronal cell bodies, indic...
متن کاملTranscriptional Coordination of Synaptogenesis and Neurotransmitter Signaling
During nervous system development, postmitotic neurons face the challenge of generating and structurally organizing specific synapses with appropriate synaptic partners. An important unexplored question is whether the process of synaptogenesis is coordinated with the adoption of specific signaling properties of a neuron. Such signaling properties are defined by the neurotransmitter system that ...
متن کاملFatty Acid Signaling in the -Cell and Insulin Secretion
Fatty acids (FAs) and other lipid molecules are important for many cellular functions, including vesicle exocytosis. For the pancreatic -cell, while the presence of some FAs is essential for glucose-stimulated insulin secretion, FAs have enormous capacity to amplify glucose-stimulated insulin secretion, which is particularly operative in situations of -cell compensation for insulin resistance. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Molecular Neuroscience
سال: 2012
ISSN: 0895-8696,1559-1166
DOI: 10.1007/s12031-012-9796-3